1KB DNA Ladder is a premixed, ready-to-load molecular weight marker containing eight linear double-stranded DNA fragments. The DNA Ladder is suitable for use as molecular weight standards for agarose gel electrophoresis. The DNA Ladder contains 1.0 -10.0 kb DNA fragments. The 4.0kb band (100 ng/5 μl) has doubled intensity than other bands to serve as reference band. https://molecular-tools.creative-enzymes.com/1kb-dna-ladder-i-item-236.html

Superoxide dismutase (SOD) catalyzes the dismutation of superoxide radicals to hydrogen peroxide and molecular oxygen. SOD plays a critical role in the defense of cells against the toxic effects of oxygen radicals. SOD competes with nitric oxide (NO) for superoxide anion (which reacts with NO to form peroxynitrite), thereby SOD promotes the activity of NO. SOD has also been shown to suppress apoptosis in cultured rat ovarian follicles, neural cell lines, and transgenic mice by preventing the conversion of NO to peroxynitrate, an inducer of apoptosis. https://diagnostic-enzymes.creative-enzymes.com/mn-superoxide-dismutase-recombinant-item-68.html

Xanthine oxidase is a form of xanthine oxidoreductase, a type of enzyme that generates reactive oxygen species. These enzymes catalyze the oxidation of hypoxanthine to xanthine and can further catalyze the oxidation of xanthine to uric acid. These enzymes play an important role in the catabolism of purines in some species, including humans. https://diagnostic-enzymes.creative-enzymes.com/xanthine-oxidase-from-arthrobacter-sp-item-64.html

In enzymology, a quinoprotein glucose dehydrogenase (EC 1.1.5.2) is an enzyme that catalyzes the chemical reaction: D-glucose + ubiquinone ↔D-glucono-1,5-lactone + ubiquinol. Thus, the two substrates of this enzyme are D-glucose and ubiquinone, whereas its two products are D-glucono-1,5-lactone and ubiquinol. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with a quinone or similar compound as acceptor. This enzyme participates in pentose phosphate pathway. It employs one cofactor, PQQ. https://diagnostic-enzymes.creative-enzymes.com/native-microorganism-glucose-dehyrogenase-pqq-dependent-item-46.html

Probiotics are living microorganisms that co-exist with the human. Different from pathogenic microorganisms, probiotics are beneficial, sometimes essential to health. For example, the intake of probiotics can increase the number of beneficial bacteria in the intestine, maintain the dynamic balance of intestinal flora, and enhance gastrointestinal health. Creative Enzymes has established a specialized production site for freeze-dried probiotics and provides custom probiotic formulation. Our probiotics products include Lactobacillus, Saccharomyces, Bifidobacterium, Lactococcus, Streptococcus, Leuconostoc, Bacillus, etc., covering food science, nutrition, microbiology, bioengineering, fermentation engineering, and other fields. https://probiotic.creative-enzymes.com/custom-probiotic-formulation.html

Leuconostoc mesenteroides is a species of lactic acid bacteria associated with fermentation, under conditions of salinity and low temperatures (such as lactic acid production in fermented sausages). In some cases of vegetable and food storage, it was associated with pathogenicity (soft rot, slime and unpleasant odor). L. mesenteroides is approximately 0.5-0.7 µm in diameter and has a length of 0.7-1.2 µm, producing small grayish colonies that are typically less than 1.0 mm in diameter. It is facultatively anaerobic, Gram-positive, non-motile, non-sporogenous, and spherical. It often forms lenticular coccoid cells in pairs and chains, however, it can occasionally forms short rods with rounded ends in long chains, as its shape can differ depending on what media the species is grown on. https://probiotic.creative-enzymes.com/leuconostoc-mesenteroides-powder-item-62.html

Bacilli are gaining interest in human-health related functional food research coupled with their enhanced tolerance and survivability under a hostile environment of the gastrointestinal tract. Besides, Bacilli are more stable during processing and storage of food and pharmaceutical preparations, making them a more suitable candidate for health-promoting formulations. Further, Bacillus strains also possess biotherapeutic potential, which is connected with their ability to interact with the internal milieu of the host by producing a variety of antimicrobial peptides and small extracellular effector molecules. https://probiotic.creative-enzymes.com/bacillus-strains.html

Our high-quality, organic, adaptogenic, finely filtered mushroom extracts can be used as nutritional supplement, in cosmetics and skin care and in agriculture. Creative Enzymes provide 20 mushroom extracts in liquid or powder form, including Tremella Fuciformis extract, Sparassis crispa extract, Schizophyllan, Cordyceps extract etc. https://www.creative-enzymes.com/cate/mushroom-extracts_91.html

A thermostable Alpha-L-Rhamnosidase (Naringinase, RhamA) that catalyzes the cleavage of the bond between terminal L (+)-rhamnose and the aglycone of rhamnose-containing glycosides. The enzyme is very active on naringin but has also substantial activity with hesperidin as substrate. https://www.creative-enzymes.com/similar/rhama_632.html

Alcohol dehydrogenases (ADH) are a group of dehydrogenase enzymes that occur in many organisms and facilitate the interconversion between alcohols and aldehydes or ketones with the reduction of nicotinamide adenine dinucleotide (NAD+ to NADH). In Humans and many other animals, they serve to break down alcohols that otherwise are toxic, and they also participate in geneRation of useful aldehyde, ketone, or alcohol groups during biosynthesis of various metabolites. In yeast, plants, and many bacteria, some alcohol dehydrogenases catalyze the opposite reaction as part of fermentation to ensure a constant supply of NAD+. https://www.creative-enzymes.com/similar/alcohol-dehydrogenase_43.html

Mutation Detection Kit provides a simple, reliable, and rapid method for the detection of site specific cleavage of genomic DNA that is extracted from cells transfected with constructs expressing engineered nucleases such as Transcription activator-like effector nucleases (TALEN), Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR)/Cas9, or Zinc-finger nucleases (ZFN). Mutation Detection Kit includes High-Fidelity DNA polymerase for amplifying the target regions from cells, and T7 Endonuclease I for recognizing and detecting the mismatches caused by gene editing tools. It provides an easy and reliable approach for estimating the efficiency of genome editing. https://molecular-tools.creative-enzymes.com/mutation-detection-kit-item-285.html

NLS-Cas9-EGFP is a fusion protein contains a nuclear localization sequence (NLS) on its N terminal and EGFP on the C terminal. The EGFP can be used as a reporter for tracking or sorting transfected cells, which enables the possibility of enriching cell populations for desired genome edits via fluorescence activated cell sorting (FACS). It significantly reduces the labor and cost associated with single cell cloning and genotyping in genome editing applications. https://molecular-tools.creative-enzymes.com/nls-cas9-egfp-nuclease-item-283.html

Cas9-C-NLS nuclease is the recombinant Streptococcus pyogenes Cas9 (wt) protein with a C-terminal nucleic localization signal (NLS). It can be used for genome editing by inducing site-specific DNA double stranded breaks. Cas9 protein forms a very stable ribonucleoprotein (RNP) complex with the guide RNA (gRNA) component of the CRISPR/Cas9 system, which can localize to the nucleus immediately once entering the cell with the guide of the NLS. https://molecular-tools.creative-enzymes.com/cas9-c-nls-nuclease-item-279.html

In enzymology, a glucose 1-dehydrogenase (EC 1.1.1.47) is an enzyme that catalyzes the chemical reaction:beta-D-glucose + NAD (P)+↔ D-glucono-1,5-lactone + NAD (P)H + H+. The 3 substrates of this enzyme are beta-D-glucose, NAD+, and NADP+, whereas its 4 products are D-glucono-1,5-lactone, NADH, NADPH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. https://diagnostic-enzymes.creative-enzymes.com/glucose-dehydrogenase-recombinant-item-28.html

Malate dehydrogenase is an enzyme in the citric acid cycle that catalyzes the conversion of malate into oxaloacetate (using NAD+) and vice versa (this is a reversible reaction). Malate dehydrogenase is not to be confused with malic enzyme, which catalyzes the conversion of malate to pyruvate producing NADPH. Malate dehydrogenase is also involved in gluconeogenesis, the synthesis of glucose from smaller molecules. Pyruvate in the mitochondria is acted upon by pyruvate carboxylase to form oxaloacetate, a citric acid cycle intermediate. https://diagnostic-enzymes.creative-enzymes.com/native-microorganism-malate-dehydrogenase-item-39.html

Lactobacillus salivarius is a probiotic bacteria species that has been found to live in the gastrointestinal tract and exert a range of therapeutic properties including suppression of pathogenic bacteria. https://probiotic.creative-enzymes.com/lactobacillus-salivarius-freeze-dried-powder-item-44.html

Lactococcus lactis is a Gram-positive bacterium used extensively in the production of buttermilk and cheese, but has also become famous as the first genetically modified organism to be used alive for the treatment of human disease. https://probiotic.creative-enzymes.com/lactococcus-lactis-freeze-dried-powder-item-45.html

Probiotics may exhibit antiallergic effects by degradation or structural modification of enteral antigens, stabilization of aberrant microbiota, improvement of the gut-barrier function, regulation of the secretion of pro-inflammatory mediators, and development of the immune system. Experimental studies have found that Antiallergic Probiotics exert strain-specific effects in the intestinal lumen and on epithelial cells and immune cells with antiallergic potential. These effects include enhancement in antigen degradation and gut barrier function and induction of regulatory and pro-inflammatory immune responses. https://probiotic.creative-enzymes.com/multi-strain-probiotics/antiallergic-formula.html

Tyrosinase is a copper-containing oxidase, which has activity for both catechols and cresol. It is responsible for browning reactions. This enzyme is reported to have two binding sites for aromatic substrates and a different binding site for oxygen-copper. https://www.creative-enzymes.com/similar/tyrosinase_700.html

A variety of enzyme purification services are available at Creative Enzymes. We provide purification and quality analysis of purified enzymes in small trial scales or large industrial scales from natural resources or production mixtures, for clinical, therapeutic, research, and chemical industries. Our services also cover the preliminary steps, as well as post-purification recovery and analysis of the purified enzymes. https://www.creative-enzymes.com/service/enzyme-purification_307.html

Creative Enzymes is a leading contract manufacturing and development company and a qualified Enzyme Producer. Our high-quality services are focused on enzyme-related projects and serve customer’s needs in many industries. We develop and manufacture speciality enzymes in both small and large quantities for various applications, such as food & beverage, chemical processing, life science, and waste management. We provide reliable quality at a competitive price, serving all processes from discovery to commercialization. https://www.creative-enzymes.com/service/industrial-enzyme-production_380.html

2×Taq PCR SuperMix is a ready-to-use mixture of Taq DNA Polymerase, dNTPs and optimized buffer. The SuperMix is provided at 2×concentration and used at 1× concentration by adding template, primers and H2O. PCR products are not suitable for directly load to PAGE. https://molecular-tools.creative-enzymes.com/2taq-pcr-supermix-item-258.html

"2×Speed Pfu PCR SuperMix (-dye ) is a ready-to-use mixture of Speed Pfu DNA polymerase, dNTPs, and optimized buffer. The SuperMix is provided at 2× concentration and can be used at 1× concentration by adding template, primers and H2O.
• 2×Speed Pfu PCR SuperMix (-dye ) offers 108-fold fidelity as compared to DNA Polymerase.
• Extension rate is about 2-6 kb/min.
• PCR products can be directly cloned into pEASY-Blunt vectors.
• Amplification of genomic DNA fragment up to 15 kb.
• Amplification of plasmid DNA fragment up to 20 kb." https://molecular-tools.creative-enzymes.com/2speed-pfu-pcr-supermix-dye-item-270.html

15K DNA Marker is a premixed, ready-to-load molecular weight marker containing eight linear double-stranded DNA fragments. The DNA Ladder is suitable for use as molecular weight standards for agarose gel electrophoresis. The DNA Ladder contains 500 bp -15.0 kb DNA fragments. The 5.0kb band (100 ng/5 μl) has doubled intensity than other bands to serve as reference band. https://molecular-tools.creative-enzymes.com/15kdna-marker-item-239.html

Native Pseudomonas sp. Lipoprotein lipase (EC 3.1.1.34) is a member of the lipase gene family, which includes pancreatic lipase, hepatic lipase, and endothelial lipase. It is a water soluble enzyme that hydrolyzes triglycerides in lipoproteins, such as those found in chylomicrons and very low-density lipoproteins (VLDL), into two free fatty acids and one monoacylglycerol molecule. It is also involved in promoting the cellular uptake of chylomicron remnants, cholesterol-rich lipoproteins, and free fatty acids. LPL requires ApoC-II as a cofactor. https://diagnostic-enzymes.creative-enzymes.com/native-pseudomonas-sp-lipoprotein-lipase-item-90.html

In enzymology, a Native Alcaligenes sp. Choline Oxidase (EC 1.1.3.17) is an enzyme that catalyzes the chemical reaction: choline + O2? betaine aldehyde + H2O2. Thus, the two substrates of this enzyme are choline and O2, whereas its two products are betaine aldehyde and H2O2. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with oxygen as acceptor. https://diagnostic-enzymes.creative-enzymes.com/native-alcaligenes-sp-choline-oxidase-item-89.html

Helicobacter pylori (H. pylori) is a spiral-shaped bacterium attached to or just above the gastric mucosa. The organism can persist in the stomach indefinitely and may not cause clinical illness many years after its infection. H. pylori is associated with the development of gastrointestinal disorders as chronic gastritis, peptic ulcer, and gastric adenocarcinoma. H. pylori is also involved in the development of other extra-gastric disorders such as mucosa-associated lymphoid tissue lymphoma (MALT), idiopathic thrombocytopenic purpura, vitamin B12 deficiency, and iron deficiency. H. pylori gastric infection is one of the most prevalent infectious diseases worldwide, with an estimate of 40%-50% of the world population. Creative Enzymes provides high-quality Antihelicobacter probiotics for academic and industrial use. https://probiotic.creative-enzymes.com/multi-strain-probiotics/anti-helicobacter-pylori-formula.html

Many clinical studies have proven the effectiveness of probiotics for treating diseases such as obesity, insulin resistance syndrome, type 2 diabetes, and non-alcoholic fatty liver disease. Furthermore, the positive effects of probiotics on human health have been demonstrated by increasing immunity. Scientific reports also show the benefits of the prophylactic use of probiotics in different types of cancer and side effects associated with cancer. We need to know how probiotics work based on the strain, dose, and components used to produce a given probiotic product. Creative Enzymes provides best probiotic for gut health for academic and industrial use. https://probiotic.creative-enzymes.com/multi-strain-probiotics/gut-health-formula.html

"Probiotics have been used to replace traditional therapies. The main mechanism of probiotics in the treatment of BV is to reconstruct the vaginal microbial environment. Common probiotics include L. reuteri RC-14, L.fermentum, L. gasseri, L. rhamnosus GR-1, L. acidophilus, and L. crispatus. Clinical trials have shown that these probiotics can play a positive role in restoring vaginal microecology and treating BV. Probiotics also avoid the abuse of antibiotics, which can cause drug-resistant bacteria to appear. Probiotics have no side effects and have great value in this application. In obstetrics and gynecology, Lactobacilli species are mainly used to restore the physiologic vaginal microbiota in order to treat bacterial vaginosis and vulvovaginal candidiasis (VVC) and prevent preterm birth. Creative Enzymes provides high-quality female probiotics for vaginal health for academic and industrial use.
" https://probiotic.creative-enzymes.com/multi-strain-probiotics/female-vaginal-health-

"Enzymes have great potentials in agriculture, biomass processing, and biofuels production. In fact, some enzymes have already brought more effectiveness while doing less harm to the environment, compared to the more traditional chemical processes. Nowadays, more and more biomass enzymes are used to improve productivity of agriculture, enhance biofuel quality, and enable economic biomass conversion. Creative Enzymes has full range of products for these applications and is open to potential co-development of new products.
" https://www.creative-enzymes.com/cate/agriculture-biomass-and-biofuels_105.html