A series of studies have confirmed that T-cell receptor (TCR) repertoire could sever as a biomarker for monitoring immune response. CD Genomics has developed a state-of-the-art high throughput sequencing method (TCR-Seq) to characterize the TCR repertoires. TCR, which locates on the surface of T cells, is responsible for the recognition of the Ag-MHC (major histocompatibility complex) molecules. The recombination of the variable (V), diversity (D), and joining (J) genes generates the immense diversity of TCR, which is critical to the adaptive immune system. In this way, the sequencing and analysis of TCR repertoire may help to obtain a better understanding of the response of adaptive immunity, and ultimately, sheds light on the discovery of novel infectious agents and holds the invaluable potential to aid in antibody or vaccine development, clinical diagnosis, treatment, and prevention. https://www.cd-genomics.com/tcr-seq.html