No obesity.
When I moved to the US in 1993, I was my ideal weight. Within 3 days I came down with the worst case of flu ever - no natural immunity to the US version of the flu.
Very shortly after recovery I began to gain weight.
Have struggled ever since.
The gut biome is important, destroy that, and the body struggles.
Compound it with food containing chemicals the body hordes and health is harder to achieve.