A protein phosphatase (PP) is an enzyme catalyzing the removal/hydrolysis of phosphate groups from phosphorylated amino acid residues (Ser, Thr and Tyr) of proteins. The process is termed dephosphorylation. There are approximately 200 phosphatases in the human proteome. Since many kinases are oncogenes, phosphatases, counterbalancing the activity of kinases, are likely to act as tumor suppressors, such as PTEN. They are essential for brain function such as learning and memory. Dysregulation of PPs is associated with disorders inducing autoimmune diseases, cognitive ageing and neurodegeneration, as well as cancer, diabetes and obesity. https://www.cd-biosciences.com/kinases-phosphatases.html