i weigh approximately 200 pounds. i take the dosage for my weight using the slide on the plunger. i take 2x that amount anytime i feel ill. i have had great success with it. i do it once a week for maintainance. if im ill i do it 5 days in a row. usually feel much better in a few hours or less. i did have an ear infection a few weeks back and had to get antibiotics from my doctor (who reccomended the ivermectin) he stated ivermectin is the safest drug on the market. safer than most vitamins. the ear infrction was the only time ivermectin didnt knock it out.