Advances in genomics have triggered a revolution in the field of discovery-based research and systems biology, and promoted the understanding of the most complex biological systems such as the brain. Genomics data analysis, transcriptomics, proteomics, and metabolomics together form the basis of omics for systems biology. The use of bioinformatics to analyze genomic data has laid a data foundation for subsequent genetic analysis, gene expression measurement, gene function identification and other further research. https://bioinfo.cd-genomics.com/genomics.html

"Metatranscriptome sequencing is a new sequencing technology that performs high-throughput sequencing on the RNA of all microorganisms in a sample in a specific period and a specific environment, and directly obtains the information of all microorganisms in that environment. Compared with metagenome, metatranscriptome contains not only microbial species information, but also microbial gene expression information. Thus, the complex microbial community changes can be studied from the transcription level, and potential new genes can be better tapped. CD Genomics uses bioinformatics to provide metatranscriptome sequencing data analysis that can analyze the dynamic changes of microbial flora comprehensively. Our high-quality metatranscriptomics pipeline data analysis platform will be used to generate high-quality analysis reports in a fast analysis cycle.
" https://bioinfo.cd-genomics.com/metatranscriptome-analysis.html

Hi-C sequencing, as known as chromosome conformation capture sequencing, short for 3C-Seq, is a next-generation sequencing (NGS) based method for interpreting the interaction patterns among different DNA sequences, as well as providing high-resolution chromatin three-dimensional structure information. https://rna.cd-genomics.com/chromosome-conformation-capture-sequencing-3c-seq.html

RNA immunoprecipitation sequencing (RIP-seq) is a next-generation sequencing (NGS)-based method to comprehensively study the situation of intracellular RNA and its binding protein, a dynamic process of the post-transcriptional regulatory network. We provide a one-stop RIP-seq service to help customers discover new RNA-protein interaction sites and explore more gene regulation functions. https://rna.cd-genomics.com/rna-immunoprecipitation-sequencing.html

CD Genomics analyzes the microbes found in air, and their impact on human health using sequencing techniques like metagenomics sequencing, 16S/18S/ITS sequencing, and metranscriptomic sequencing. RT-qPCR is also used for achieving the qualitative and quantitative analysis of DNA or RNA. Bioinformatics analysis is required to process raw reads and determine the taxonomic classifications, biological functions for ecological environment, and effects on human health. https://www.cd-genomics.com/microbioseq/microbial-diversity-in-the-air.html

The gut microbiota represents a thriving and intricate community of symbiotic microbes inhabiting the animal gastrointestinal tract. Comparable to an organ in its own right, gut microbiota conduct a plethora of physiological functions that encompass metabolism, immunological regulation, and endocrine operations. Beneficial microbes play a cardinal role in normal gut functionality: they aid in moisture absorption, vitamin synthesis, the mitigation of harmful substances, and the prevention of pathogenic invasion. In contrast, an excess of harmful microbes can lead to invasive pathogens, alterations in gut motility, production of detrimental substances, and poor waste excretion. CD Genomics proffers leading-edge, integrated research solutions for the study of gut microbiota, employing advanced metabolomics and high-throughput sequencing technologies. https://www.cd-genomics.com/microbioseq/gut-microbiome-research.html

As a leading provider of NGS services and a partner of Illumina, CD Genomics offers a portfolio of solutions for metagenomics sequencing. 16S amplicon sequencing is characterized by cost-efficiency, high-speed and practicability to help you identify and investigate the microbial community. With over 10 years of experience, we can totally meet your project requirements and budgets in the exploration of microbial biodiversity. https://www.cd-genomics.com/16s-18s-its-amplicon-sequencing.html

Genome assembly is one of the main purposes of sequencing. De novo genome assembly is a strategy for genome assembly, representing the genome assembly of a novel genome from scratch without the aid of reference genomic data. De novo genome assemblies assume no prior knowledge of the source DNA sequence length, layout or composition. https://www.cd-genomics.com/a-guide-to-de-novo-genome-assembly.html

CD Genomics is committed to offering advanced next generation sequencing (NGS) strategy to help researchers screening the phage display libraries in a high-throughput manner, enabling you to preserve the diversity of antibody libraries and quickly select the plurality of related antibodies as well as rare phages in a large population that can be recovered and tested for activity. Illumina deep-sequencing provides many advantages to phage display library screening, especially for the large sequence collection. https://www.cd-genomics.com/antibody-screening-sequencing.html

A service provider for the whole exome data analysis, CD Genomics uses bioinformatics to deeply mine the genetic information in the coding region based on the whole exome sequencing data. Our unique skills in data analysis can meet customers' personalized data analysis needs and provide you with comprehensive data analysis results. https://bioinfo.cd-genomics.com/whole-exome-data-analysis.html

A variant detection and analysis service provider, CD Genomics uses bioinformatics to help you explore the genetic variation and decipher the essence of life. Our unique skills in data analysis can meet customers' personalized data analysis needs and provide you with comprehensive data analysis. https://bioinfo.cd-genomics.com/variant-detection-and-analysis.html

UMI small RNA sequencing (RNA-seq) is a unique molecular identifier (UMI)-based technology for accurate qualitative and quantitative analysis of multiple small RNAs in cells. PCR amplification bias can be removed by adding UMI into each cDNA segment, achieving accurate and unbiased quantification. UMI small RNA-seq can accurately identify SNP, quantify low-abundance transcripts, and reveal comprehensive transcriptome information. We provide UMI small RNA-seq to help you analyze microRNA (miRNA), small interfering RNA (siRNA), piwi-interacting RNA (piRNA) at one time. https://rna.cd-genomics.com/umi-small-rna-seq.html

Total RNA sequencing (RNA-seq) is a next-generation sequencing (NGS)-based method to capture a comprehensive view of the transcriptome. We provide total RNA-seq to help you analyze coding RNAs and multiple forms of ncRNA, including long noncoding RNA (lncRNA), small nuclear (snRNA), small nucleolar (snoRNA), and other ncRNA species. https://rna.cd-genomics.com/total-rna-seq.html

Poly(A) RNA sequencing (RNA-seq) is a next-generation sequencing-based method to comprehensively analyze RNAs with poly(A) tails such as message RNAs (mRNAs) and long non-coding RNAs (lncRNAs). This technique accurately reveals the level of gene expression in your biological sample under specific conditions and generates a complete picture of the transcriptome for the identification of novel alternative splicing, transcripts, gene fusion events, etc. https://rna.cd-genomics.com/polya-rna-seq.html

Our excellent microbial identification platform (including Rep-PCR, MicroSEQ®, NGS-based microbial identification, multi-locus sequence typing, and mycoplasma detection) aims to identify microbial species efficiently and economically in a fast high-throughput, and simple manner. We deliver high-accuracy and high-sensitivity data to help your microbial and laboratory research. https://www.cd-genomics.com/microbioseq/microbial-identification.html

Our Metranscriptomics platform elucidates three aspects of a microbial community, including gene activity diversity, gene expression abundance, and differential gene expression analysis by utilizing the most advanced next and third generation sequencing technologies and integrated bioinformatics analysis. The gene expression analysis can tell which genes exhibit the highest change in expression levels in different conditions to identify potential biomarkers and expression signatures. https://www.cd-genomics.com/microbioseq/metatranscriptomics.html

Our microbial diversity analysis platform based on 16S/18S/ITS amplicon sequencing aims to characterize microbial diversity efficiently and economically by utilizing the next/third generation sequencing technology and other molecular technologies. Our scientists utilize this platform to assist our customers for meeting both scientific and regulatory requirements. https://www.cd-genomics.com/microbioseq/microbial-diversity-analysis.html

CD Genomics is committed to providing novel NGS services enabling researchers to explore structure and function of the microbial community in a high-resolution and culture-independent manner using technology from Illumina and PacBio. In addition, we also offer the service to sequence the genome of the individual cultured bacteria, fungi, phage or virus, whether do novo or re-sequencing. https://www.cd-genomics.com/microbial-genomics.html

CD Genomics offers the transcriptome-wide analysis of the location of m6A in mRNA transcripts and other RNAs by methylated RNA immunoprecipitation sequencing (MeRIP-seq). MeRIP-seq uses an antibody that specifically detects and characterizes of N6-methyladenosine (m6A) in RNA. As 3'UTR of mRNA plays important role in mRNA stability, localization, and translation, and may affect the binding of RNA-regulatory proteins to these regions, enrichment of m6A in this region indicates that m6A may affect RNA metabolism and gene expression. Inhibition of the enzymes that involve in the RNA methylation has also provided clues to the potential biological roles of this modification. Hence, the identification and characterization of modified bases in RNA may lead to a better understanding of biological pathways. https://www.cd-genomics.com/merip-sequencing.html

ChIP-Seq (chromatin immunoprecipitation sequencing), which refers to the binding site analysis, is a way to analyze DNA-protein interactions. The technique combines chromatin immunoprecipitation (ChIP) with NGS to identify where the DNA binds to the associated proteins. It can be used to pinpoint the binding sites of any interested protein throughout the genome. ChIP-seq is often used to determine how transcription factors and other chromatin-related proteins affect phenotypic mechanisms. https://www.cd-genomics.com/chip-seq.html

CD Genomics provides bacterial de novo sequencing data analysis. Using bioinformatics to explore the whole genome sequence map of bacteria in one step, our unique data analysis skills and advanced software tools can meet our customers' personalized data analysis needs and provide you with easy-to-interpret data analysis reports. https://bioinfo.cd-genomics.com/bacterial-de-novo-sequencing-analysis.html

As one of the group evolution analysis providers, CD Genomics uses bioinformatics to help you analyze the population information and reveal the process of population evolution quickly and accurately. Our unique data analysis skills can meet customers' personalized data analysis needs and provide the most easy-to-interpret data analysis reports. https://bioinfo.cd-genomics.com/group-evolution-analysis.html

CD Genomics provides a battery of biofluid profiling services utilizing next-generation sequencing technology. Our services can complement mainstream sequencing methods to investigate the levels of RNA molecules in biofluid samples, explore poorly characterized, rare transcripts and mutations. Cell-free RNA sequencing (RNA-seq) is a tool that extracts, processes, and analyzes cell-free RNA. We have developed a complete, automated workflow for performing cell-free RNA-seq. Our services are fully customizable to your research needs. https://rna.cd-genomics.com/cell-free-rna-seq.html

Next-generation sequencing (NGS)-based methods, either relying on antibody enrichment or third-generation sequencing, have been developed to map post-transcriptional RNA modification and explore their functions, We provide a full range of epitranscriptomics services to investigate RNA modifications using NGS or long-read sequencing (Oxford nanopore sequencing and PacBio SMRT sequencing). We can help you detect many forms of RNA modifications including m7G, m3C, m1A, 5mC, 5hmC, m6A, m6Am, acetylation, and 2'-O-methylation. https://rna.cd-genomics.com/epitranscriptomics.html

Viral metagenomic studies have provided insights into viral ecology by elucidating the genetic potential, community structure, and biogeography of environmental viruses. Viral metagenomics has expanded current knowledge on virus-host interactions by uncovering genes that may allow the viruses to manipulate their hosts in unexpected ways. The intrinsic potential for virus discovery through viral metagenomics can help advance a wide array of disciplines including evolutionary biology, pathogen surveillance, and biotechnology. In addition, functional viral metagenomics serves as a platform to discover more useful enzymes. As the annotation of viral genes continues to improve, the discovery of vital enzymes will increase considerably. https://www.cd-genomics.com/microbioseq/viral-metagenomics.html

Fungi, a large group of eukaryotes, consist of microorganisms such as yeast and mold, as well as the mushrooms. Many beneficial fungi have important nutritional and medicinal value. However, some pathogenic fungi can cause disease in humans, animals, or plants. With the maturity of high-throughput sequencing technologies, the cost of genome sequencing has been greatly reduced, making it possible to sequence fungal genomes quickly and economically. Fungal whole genome sequencing allows us to obtain the genome sequence of fungi and study their structure and function. https://www.cd-genomics.com/microbioseq/fungal-whole-genome-sequencing.html

Long-read sequencing technologies, including PacBio SMRT and Oxford Nanopore sequencing, make it possible to detect variants in genomic regions that are proposed difficult to map through typical short-read sequencing methods (such as Illumina sequencing). CD Genomics is a leading global life sciences company. We specialize in the application of third-generation sequencing technologies. With the help of our advanced platform and skilled experts, researchers can detect all variant types from long-read datasets and discover new variants in complex genomic regions. https://longseq.cd-genomics.com/variant-calling.html

CD Genomics is a leading provider of genomic services. We have extensive experience in long-read amplicon sequencing using the PacBio platform. PacBio SMRT long-read sequencing is capable of generating complete, uniform, unbiased coverage spanning long amplicons, allowing for a more realistic restoration of the microbial community structure in the samples. 16S/18S/ITS amplicon sequencing, also known as microbial diversity sequencing, refers to the sequencing of PCR products from specific regions such as 16S ribosomal DNA (rDNA), 18S rDNA, Internal Transcribed Spacer (ITS), and functional genes. This method does not require culturing microorganisms, and by detecting sequence variation and abundance in the target region, information on microbial community structure, evolutionary relationships, and microbial relevance to the environment can be obtained from environmental samples. https://www.cd-genomics.com/longseq/full-length-16s-18s-its-amplicon-sequencing.html

The identification of microorganisms has relied on phenotypic methods at early eras. With advances in genetic methods, various classification methodologies based on nucleotide sequences are increasingly popular due to their specificity and speed. Gene sequencing-based techniques can serve to detect, identify, and monitor microbes, even poorly known or uncultured microorganisms. https://www.cd-genomics.com/microbial-identification-1.html

CD Genomics is proud to provide genotyping by sequencing service to advance your population based genotyping studies in an effective and economic way. Please contact us for more information and a detailed quote. CD Genomics is the licensed service provider for this technology. Keygene N.V. owns patents and patent applications protecting its Sequence Based Genotyping technologies. https://www.cd-genomics.com/genotyping-by-sequencing-gbs.html