Herpes virus (HSV) is a widespread infection in humans and animals, causing diseases such as herpes epithelial keratitis (HEK). It is primarily caused by HSV-1 infection, a viral infection that poses a significant threat to ocular health because the virus can lurk in the trigeminal nerve and can lead to recurrent attacks and blindness. To cater to the scientific demands in this domain, we offer specialized rabbit models of HSV-infected corneal keratitis, with a focused aim to deepen our understanding of HSV-induced keratitis pathogenesis and to pioneer effective therapeutic strategies. https://antiviral.creative-diagnostics.com/rabbit-corneal-keratitis-model-infected-with-hsv.html

LPS is dispersable in aqueous solvents at concentrations of 1mg/ml. To achieve suspension in water, heating to about 50°C with intermittent vortexing or sonication is generally recommended. Allow ample time for dispersion to occur. The use of 0.5% triethylamine aids in dispersion. Triethylaine is very basic and may be neutralized with Tris HCl to avoid hydrolysis of the fatty acid chains. https://www.creative-diagnostics.com/E-coli-O157-H7-LPS-243675-385.htm

The Entamoeba histolytica Ag ELISA is a device for direct detection of Entamoeba histolytica specific antigen in faecal samples. https://www.creative-diagnostics.com/E-histolytica-EIA-Kit-241402-466.htm

Creative Diagnostics is striving to develop high-quality detection reagents to support the development of anticoccidial detection. After years of research and experience by our technicians, we successfully developed a series of antigens and antibodies for immunoassays, and established the enzyme-linked immunosorbent assay (ELISA) and lateral flow immunoassay (LFIA) detection platforms. https://www.creative-diagnostics.com/food-analysis/tag-diaveridine.html

Creative Diagnostics is striving to develop high-quality detection reagents to support the development of anticoccidial detection. After years of research and experience by our technicians, we successfully developed a series of antigens and antibodies for immunoassays, and established the enzyme-linked immunosorbent assay (ELISA) and lateral flow immunoassay (LFIA) detection platforms. https://www.creative-diagnostics.com/food-analysis/tag-clopidol.html

Host cells for biologics production contain hundreds of unique HCPs that are considered a potentially dangerous contaminant when present in the final product. How can HCPs be adequately measured and characterized to monitor and control residual impurities in products? A widely used method is to detect HCP by immunoassay using anti-HCP antibodies. https://qbd.creative-diagnostics.com/products/anti-hcp-antibodies.html

Our range of NeutraAbTM Brucella antibodies can be used for applications including neutralization assay and ELISA. Please use the filters to sort the attributes in the table below in order to find the antibody that fits your exact requirements. Our proprietary cloning platform allows us to produce high-quality recombinant versions of these antibodies which will be valuable reagents for research and diagnostics. If you need any further assistance, please do not hesitate to contact us. https://antiviral.creative-diagnostics.com/brucella-antibodies.html

Lysosomes are a membrane-bound organelle found in many animal cells. They are spherical vesicles containing hydrolases that break down many biomolecules. The pH of the lysosome in the range of 4.5 to 5.0 is optimal for the enzyme involved in the hydrolysis. Lysosomes perform waste treatment functions by digesting unused or unused materials from the cytoplasm inside and outside the cell. Among them, substances from outside the cell are absorbed by endocytosis, while substances from inside the cell are digested by autophagy. https://www.creative-diagnostics.com/blog/index.php/lysosomal-storage-disease/

Carcinoembryonic antigen (CEA) is a glycoprotein involved in cell adhesion. It is normally produced during fetal development, but the production of CEA stops before birth. Therefore, it is not usually present in the blood of healthy adults, although levels are raised in heavy smokers. CEA is a glycosyl phosphatidyl inositol (GPI)-cell surface anchored glycoprotein whose specialized sialofucosylated glycoforms serve as functional colon carcinoma L-selectin and E-selectin ligands, which may be critical to the metastatic dissemination of colon carcinoma cells. https://www.creative-diagnostics.com/Human-CEA-protein-258494-422.htm

Creative Diagnostics is striving to develop high-quality detection reagents to support the development of antibiotic detection. After years of research and experience by our technicians, we successfully developed a series of antigens and antibodies for immunoassays, and established the enzyme-linked immunosorbent assay (ELISA) and lateral flow immunoassay (LFIA) detection platforms. https://www.creative-diagnostics.com/food-analysis/tag-ofloxacin.html

We provide raw material reagents and analytical services for quality control of biological drugs and other process-related impurity testing. https://qbd.creative-diagnostics.com/products/antibiotics-elisa-kits.html?opl=1

The antibody specificity was determined by measuring cross-reactivity (CR) with other structural analogs. The result shows that the IC50 of RHA™ anti-Ofloxacin monoclonal antibody, clone OFX was 1.17 ng/mL. The CR with pefloxacin was 9.345%, the CR with lomefloxacin, norfloxacin, pazufloxacin, enrofloxacin, ciprofloxacin, enoxacin, tusofloxacin, and nadifloxacin were all

Antigens and antibodies have been extensively validated and characterized. The antigens were analyzed by UV–Vis spectroscopy and sodium dodecyl sulfate–polyacrylamide gel electrophoresis (SDS-PAGE). The antibody sensitivity was determined by measuring the 50% inhibition concentration (IC50) by icELISA. The antibody specificity was determined by measuring cross-reactivity (CR) with other structural analogs. The result shows that the IC50 of RHA™ anti-Enrofloxacin monoclonal antibody, clone ENOR was 0.0303 ng/mL. https://www.creative-diagnostics.com/food-analysis/tag-enrofloxacin.html

Ciprofloxacin Test Reagents
Creative Diagnostics is striving to develop high-quality detection reagents to support the development of antibiotic detection. After years of research and experience by our technicians, we successfully developed a series of antigens and antibodies for immunoassays, and established the enzyme-linked immunosorbent assay (ELISA) and lateral flow immunoassay (LFIA) detection platforms.
https://www.creative-diagnostics.com/food-analysis/tag-ciprofloxacin.html

NeutraAb™ Anti-Bundibugyo Virus Glycoprotein Monoclonal Antibody
Mouse Anti-Bundibugyo Virus Glycoprotein Monoclonal Antibody for Neut, ELISA
https://antiviral.creative-diagnostics.com/p/bundibugyo-virus-glycoprotein-antibody-cabt-ns1019-457.html

NeutraAb™ Anti-HPIV3 Monoclonal Antibody
Mouse Anti-HPIV3 Monoclonal Antibody for Neut, ELISA
https://antiviral.creative-diagnostics.com/p/hpiv3-antibody-cabt-ns1268-547.html

Creative Diagnostics is striving to develop high-quality detection reagents to support the development of antibiotic detection. After years of research and experience by our technicians, we successfully developed a series of antigens and antibodies for immunoassays, and established the enzyme-linked immunosorbent assay (ELISA) and lateral flow immunoassay (LFIA) detection platforms. https://www.creative-diagnostics.com/food-analysis/tag-gamithromycin.html

Antimicrobial susceptibility test is an experimental method to detect the sensitivity of test bacteria to antimicrobial drugs. Antimicrobial susceptibility test is mainly used to detect whether antimicrobial drugs have an inhibitory effect on pathogenic microorganisms in vitro. And then this can be used clinically to guide the selection of therapeutic drugs and to understand the changes in the resistance of common pathogens in the region. Knowledge of antibiotics that are sensitive to bacteria can transform the choice of antibiotics from empirical therapy to targeted therapy. https://antiviral.creative-diagnostics.com/antimicrobial-susceptibility-testing.html

Certain viruses can agglutinate the red blood cells inside specific animals, which is defined as viral hemagglutination. A hemagglutination assay (HA) is designed to speculate a virus in the tested materials and test whether this reaction is specific. However, the ability of a virus to agglutinate red blood cells can be inhibited by corresponding particular antibodies, which leads to the development of hemagglutination inhibition assay (HAI). https://antiviral.creative-diagnostics.com/hemagglutination-assay-ha.html

Multiple sclerosis (MS), also known as encephalomyelitis disseminate, is a potentially disabling neurodegenerative disease. In MS, the immune system attacks the protective sheath (myelin) that covers nerve fibers and causes communication problems between your brain and the rest of your body. Eventually, the disease can cause permanent damage or deterioration of the nerves.

Signs and symptoms of MS vary widely and depend on the amount of nerve damage and which nerves are affected. Specific symptoms can include double vision, blindness in one eye, muscle weakness and trouble with sensation or coordination. https://reagents.creative-diagnostics.com/research-area/multiple-sclerosis.html

Antibody development is the entire process of generating and characterizing an antibody. It starts with injecting an antigen of interest into laboratory animals, allowing the immune system to develop large quantities of antibodies.

Our antibody development and screening services can provide multiple types of antibodies according to your needs. we are able to generate a large number of diverse, high-affinity antibodies towards your target antigen with industry-leading turnaround times and competitive pricing. https://www.creative-diagnostics.com/ivd-materials/services/antibody-development.html

Creative Diagnostics is striving to develop high-quality detection reagents to support the development of antibiotic detection. After years of research and experience by our technicians, we successfully developed a series of antigens and antibodies for immunoassays, and established the enzyme-linked immunosorbent assay (ELISA) and lateral flow immunoassay (LFIA) detection platforms. https://www.creative-diagnostics.com/food-analysis/tag-clindamycin.html

The large number of protein impurities generated by cell expression systems is a challenge in biopharmaceutical manufacturing processes. These proteins, called HCP, must be removed during the product purification process or they may compromise the safety and efficacy of the biologic.

Comprehensive and accurate sample characterization and complementary analysis using orthogonal methods are key to HCP detection and removal. Creative Diagnostics provides two-dimensional characterization methods for HCP samples and complement immunoassays for HCP with a range of orthogonal methods, equipping our customers with advanced equipment and experienced researchers for reliable HCP monitoring.
https://qbd.creative-diagnostics.com/services/hcp-analytical-services.html

The measurement is usually carried out on planktonic bacteria (free floating). The MIC value can be determined based on the optical density based on the use of a spectrophotometer or disk diffusion method. This is a time and cost saving strategy for screening and identifying promising drug candidates. The assay can also be adjusted to determine the minimum test concentration required to inhibit the growth of a group of test isolates (MIC50 and MIC90) that are 50% or 90%. https://antiviral.creative-diagnostics.com/minimum-inhibitory-concentration.html

Given all respiratory illnesses share some similar symptoms, it is not possible to identify the source of an infection based on clinical presentation alone. Combo rapid antigen tests for COVID-19, Flu A/B and RSV can provide with quick, accurate detection within a single test. Creative Diagnostics has several highly sensitive pairs for SARS-CoV-2, Flu A, Flu B and RSV that are ideal for use in a combo rapid COVID-19 assay. In addition, its antibody pair for SARS-CoV-2 is capable of detection of the new highly transmissible Omicron BA.2 variants. https://www.creative-diagnostics.com/ivd-materials/sars-cov-2-flu-a-flu-b-rsv-antibody-pairs.htm

Creative Diagnostics is striving to develop high-quality detection reagents to support the development of antibiotic detection. After years of research and experience by our technicians, we successfully developed a series of antigens and antibodies for immunoassays, and established the enzyme-linked immunosorbent assay (ELISA) and lateral flow immunoassay (LFIA) detection platforms. https://www.creative-diagnostics.com/food-analysis/tag-neomycin.html

HAI is closely related to HA analysis, mainly through antiviral antibodies as "inhibitors" that interfere with the interaction of viruses and RBCs. The purpose is to characterize the concentration of antibodies in antiserum or other samples containing antibodies. HAI assay is usually performed by creating antiserum dilutions serially in each well of a 96-well microtiter plate. A standard amount of virus or bacteria will be added to each well, and the mixture will be incubated at room temperature. It is necessary to set up a negative control without adding virus for each sample. During the incubation, the antibody will bind to the virus particles. If the antibody concentration and its binding affinity are sufficiently high, the blood coagulation reaction can be effectively blocked. https://antiviral.creative-diagnostics.com/hemagglutination-inhibition-assay-hai.html

Rabies is a fatal zoonotic disease of serious public health and economic significance worldwide. The rabies virus glycoprotein (RVG) has been the major target for subunit vaccine development, since it harbors domains responsible for induction of virus-neutralizing antibodies, infectivity, and neurovirulence. https://www.creative-diagnostics.com/anti-rvg-igg-elisa-kit-269750-466.htm

Parathyroid Hormone (pTH) (1-34), is a peptide fragment of the naturally occurring human parathyroid hormone and is secreted from cells of the parathyroid glands and finds its major target cells in bone and kidney. It is an important regulator of calcium and phosphorus metabolism, playing a role in calcium homeostasis of bone, kidney, breast, and placenta. pTH (1-34) administration suppresses cardiovascular calcification and down-regulates aortic osteogenic programs driven by diabetes and dyslipidemia. This ELISA was developed with serum from rabbits immunized with pTH (1-34) coupled to a carrier protein.
Immunogen: Synthetic peptide: H-Ser-Val-Ser-Glu-Ile-Gln-Leu-Met-His-Asn-Leu-Gly-Lys-His-Leu-Asn-Ser-Met-Glu-Arg-Val-Glu-Trp-Leu-Arg-Lys-Lys-Leu-Gln-Asp-Val-His-Asn-Phe-OH (Disulfide bond) coupled to carrier protein. https://www.creative-diagnostics.com/PTH-Teriparatide-EIA-Kit-238262-501.htm

High level of GDF-15 has critical role in development and progression of cardiovascular diseases such as heart failure (HF), coronary artery diseases, atrial fibrillation, diabetes, and cancer. Elevated GDF-15 level is a significant feature of cancers including breast, colon, pancreas, and prostate.Thus, GDF-15 measurement aids the diagnosis and management of cancer. https://www.creative-diagnostics.com/ivd-materials/products-growth-differentiation-factor-15-gdf-15-239.htm