Is it or is instead the difference between ignorance and willful ignorance? I had ignorance to certain Truths in my life before, but I never rejected them outright because mainstream told me they were untrue....I needed more investigation and Holy's Spirit's guidance alone with my own personal tribulation experiences.

You are right. The meme should read willful ignorance. There is a difference and accountability between innocent ignorance and willful ignorance. There is truth to the saying.. “ignorance is bliss - the more I discover about this evil world we live in my bliss has turned into a deeper sorrow, faith and hope of a better future!