Suramin: an anticancer drug with a unique mechanism of action - PubMed
We administered suramin, an anti-parasitic drug and reverse transcriptase inhibitor, to 15 patients with metastatic cancer. This compound is known to inhibit the binding of growth factors (eg, epidermal growth factor [EGF], platelet-derived growth factor [PDGF], tumor growth factor-beta [TGF-beta]) ..
https://pubmed.ncbi.nlm.nih.gov/2926472/