Always looking to be a blessing ;)
Just nosing around and came across this new article. Has a paywall so I cannot read it, but rather share to suggest this seems to still be an active research area.
https://www.nature.com/articles/s44222-024-00267-1
Integrating metabolism and evolution towards the realization of synthetic life | Nature Reviews Bioengineering
Recognition of life as a dynamic, non-equilibrium and evolvable process suggests that the realization of synthetic life could be achieved by the in vitro integration of metabolic and evolutionary processes.
https://www.nature.com/articles/s44222-024-00267-1