Yes VP Vance CAN BE THE SENATE MAJORITY LEADER! It happened 200 years ago
https://www.newsweek.com/jd-vance-vice-president-senate-majority-leader-charlie-kirk-1983232
Can JD Vance Be VP and Senate Majority Leader? Charlie Kirk Floats the Idea - Newsweek
While the Senate Majority Leader is traditionally a sitting senator, conservative commentator Charlie Kirk proposed the idea that JD Vance could take the job.
https://www.newsweek.com/jd-vance-vice-president-senate-majority-leader-charlie-kirk-1983232