Key stages in the development of antibodies are outlined in our PreciAbTM platform as follows:
Combining structure- and homology-based modeling techniques to create antibody structures
Optimization of structure by loop modeling, rotamer library, dynamics simulation, and other methods.
Identification of the complementarity-determining region (CDR) based on the antibody's tertiary structure
Modeling and analysis of antibody-antigen complexes and interactions
Identification of paratopes and epitopes as well as study of critical residues
For more: https://www.creative-biolabs.com/preciab/preciab-platform.htm