Mitochondrial health is an indicator of overall cell health

Healthy mitochondria exhibit a difference in electrical potential across the lipid bilayer that surrounds them, and some fluorescent dyes will accumulate inside mitochondria as long as this potential difference is maintained.

https://www.thermofisher.com/uk/en/home/life-science/cell-analysis/cell-analysis-learning-center/molecular-probes-school-of-fluorescence/imaging-basics/labeling-your-samples/mitochondrial-labeling.html

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